zabbix22 is the 2.2 generation of Zabbix. Notes for an upgrade are available:
http://pkgs.fedoraproject.org/cgit/zabbix22.git/plain/zabbix-fedora-epel.README?h=el5
https://www.zabbix.com/documentation/2.2/manual/installation/upgrade_notes_220
Also make sure to read the upgrade notes for all 2.2 point releases!
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This update has been submitted for testing by volter.
This update has been obsoleted by https://admin.fedoraproject.org/updates/zabbix22-2.2.5-2.el5